If you want me to tell you what happened on the level of "physics" substantially, like if it affected DNA, how sin is transmitted through birth and stuff like that, then my answer will be "I do not know". We know that as a result of the fall the human spirit was deadened, human soul was corrupted and the human body became subject to sickness and death. But all the metaphisics are not covered in the Word. I would say that the best portion in the Bible about the effects of sin is Rom. 1-3.
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Most men pursue pleasure with such breathless haste that they hurry past it. Soren Kierkegaard
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